Ultra-fast oscillation detection in EEG signal from deep-brain microelectrodes.
Annu Int Conf IEEE Eng Med Biol Soc
; 2021: 265-268, 2021 11.
Article
in En
| MEDLINE
| ID: mdl-34891287
ABSTRACT
For the last decades, ripples 80-200Hz (R)and fast ripples 200-500Hz (FR) were intensively studied as biomarkers of the epileptogenic zone (EZ). Recently, Very fast ripples 500-1000Hz (VFR) and ultra-fast ripples 1000-2000Hz (UFR) recorded using standard clinical macro electrodes have been shown to be more specific for EZ. High-sampled microelectrode recordings can bring new insights into this phenomenon of high frequency, multiunit activity. Unfortunately, visual detection of such events is extremely time consuming and unreliable. Here we present a detector of ultra-fast oscillations (UFO, >1kHz). In an example of two patients, we detected 951 UFOs which were more frequent in epileptic (8.6/min) vs. non-epileptic hippocampus (1.3/min). Our detection method can serve as a tool for exploring extremely high frequency events from microelectrode recordings.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Epilepsy
/
Brain Waves
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Annu Int Conf IEEE Eng Med Biol Soc
Year:
2021
Document type:
Article