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Specific mutations in the HIV-1 G-tract of the 3'-polypurine tract cause resistance to integrase strand transfer inhibitors.
Hachiya, Atsuko; Kubota, Mai; Shigemi, Urara; Ode, Hirotaka; Yokomaku, Yoshiyuki; Kirby, Karen A; Sarafianos, Stefan G; Iwatani, Yasumasa.
Affiliation
  • Hachiya A; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
  • Kubota M; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
  • Shigemi U; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
  • Ode H; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
  • Yokomaku Y; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
  • Kirby KA; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
  • Sarafianos SG; Children's Healthcare of Atlanta, Atlanta, GA, USA.
  • Iwatani Y; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
J Antimicrob Chemother ; 77(3): 574-577, 2022 02 23.
Article in En | MEDLINE | ID: mdl-34894227
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / HIV Integrase Inhibitors / HIV Integrase Limits: Humans Language: En Journal: J Antimicrob Chemother Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / HIV Integrase Inhibitors / HIV Integrase Limits: Humans Language: En Journal: J Antimicrob Chemother Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United kingdom