Echinocandins and Their Activity against Aspergillus terreus Species Complex: a Novel Agar Screening Method.
Antimicrob Agents Chemother
; 66(2): e0190921, 2022 02 15.
Article
in En
| MEDLINE
| ID: mdl-34902268
ABSTRACT
We evaluated the newly proposed agar screening method for echinocandin susceptibility testing of 144 Aspergillus section Terrei isolates compared with the Etest method. Both methods defined the isolates to be wild-type strains for anidulafungin and micafungin, with Etest minimal effective concentrations (MECs) of ≤0.004 mg/L. For caspofungin, the novel agar screening method identified 37 isolates to be caspofungin non-wild type based on their fluffy colony appearance on caspofungin agar. Etest MECs for caspofungin for these isolates were scattered widely from 0.002 to 0.750 mg/L, showing only partial accordance between the two methods.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Echinocandins
/
Antifungal Agents
Type of study:
Diagnostic_studies
/
Screening_studies
Language:
En
Journal:
Antimicrob Agents Chemother
Year:
2022
Document type:
Article
Affiliation country:
Austria