Primary gastrointestinal anaplastic large cell lymphoma: A critical reappraisal with a systematic review of the world literature.
J Cancer Res Ther
; 17(6): 1307-1313, 2021.
Article
in En
| MEDLINE
| ID: mdl-34916358
ABSTRACT
Anaplastic large cell lymphoma (ALCL) is a distinct T-cell non-Hodgkin lymphoma involving both nodal and extra-nodal sites with a specific anaplastic lymphoma kinase 1 (ALK-1) gene rearrangement. The commonly involved extranodal sites include skin, bone, soft tissue, lungs, and liver. ALCL primarily involving gastrointestinal (GI) tract is rare. In this manuscript, we describe a case of primary esophageal ALK1 positive-ALCL (null phenotype) in a young female, who presented with fleshy mucosal lesion in the lower third of the esophagus and present a systematic review of 35 cases of GI-ALCL reported in the English literature over the past 28 years (1990-2018) with regard to the clinicopathological characteristics, therapy, and outcome.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antineoplastic Combined Chemotherapy Protocols
/
Lymphoma, Large-Cell, Anaplastic
/
Gastrointestinal Neoplasms
Type of study:
Prognostic_studies
/
Systematic_reviews
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
J Cancer Res Ther
Journal subject:
NEOPLASIAS
/
TERAPEUTICA
Year:
2021
Document type:
Article
Affiliation country:
India