CircGOT1 promotes cell proliferation, mobility, and glycolysis-mediated cisplatin resistance via inhibiting its host gene GOT1 in esophageal squamous cell cancer.

Zhou, Shasha; Guo, Zhiyuan; Lv, Xueli; Zhang, Xueqiang

Zhou, Shasha; Guo, Zhiyuan; Lv, Xueli; Zhang, Xueqiang.

Affiliation

Zhou S; Department of Oncology, Hebei Medical University, Shijiazhuang, P.R. China.
Guo Z; Department of Oncology, Handan Central Hospital, Handan, P.R. China.
Lv X; Department of Oncology, Handan Central Hospital, Handan, P.R. China.
Zhang X; Department of Oncology, Shexian Hospital, Shexian, P.R. China.

Cell Cycle ; 21(3): 247-260, 2022 02.

Article in En | MEDLINE | ID: mdl-34919012

Subject(s)

Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; MicroRNAs; Animals; Aspartate Aminotransferase, Cytoplasmic/genetics; Aspartate Aminotransferase, Cytoplasmic/metabolism; Carcinoma, Squamous Cell/genetics; Cell Line, Tumor; Cell Movement/genetics; Cell Proliferation/genetics; Cisplatin/metabolism; Cisplatin/pharmacology; Cisplatin/therapeutic use; Epithelial Cells/metabolism; Esophageal Neoplasms/metabolism; Esophageal Squamous Cell Carcinoma/metabolism; Gene Expression Regulation, Neoplastic/genetics; Glycolysis/genetics; Humans; Mice; MicroRNAs/genetics; MicroRNAs/metabolism

Key words

GOT1; circgot1; cisplatin resistance; esophageal squamous cell cancer; glycolysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Esophageal Neoplasms / Carcinoma, Squamous Cell / MicroRNAs / Esophageal Squamous Cell Carcinoma Limits: Animals / Humans Language: En Journal: Cell Cycle Year: 2022 Document type: Article Country of publication: United States

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