Long-term Outcomes of Cataract Surgery in Patients with Retinitis Pigmentosa.
Ophthalmol Retina
; 6(4): 268-272, 2022 04.
Article
in En
| MEDLINE
| ID: mdl-34923176
ABSTRACT
PURPOSE:
To investigate the long-term outcomes of cataract surgery in patients with retinitis pigmentosa (RP).DESIGN:
Retrospective, observational study.PARTICIPANTS:
Sixty-four patients with typical RP (22 men, 42 women; average age, 62.8 ± 10.1 years) who underwent cataract surgery at Kyushu University Hospital between May 2007 and October 2015 and were followed up for ≥3 years after the surgery.METHODS:
Differences between presurgery and postsurgery visual function, including best-corrected visual acuity (BCVA) and parameters in the Humphrey field analyzer (HFA) examination using the central 10-2 program, were investigated. The presurgery conditions of the foveal ellipsoid zone (EZ) were classified into 3 grades (grade 1 invisible; grade 2 abnormal; grade 3 normal) based on OCT findings. MAIN OUTCOMEMEASURES:
BCVA, the retinal sensitivity in the HFA 10-2 test.RESULTS:
Cataract surgery was performed in 96 eyes, with an average follow-up period of 5.8 ± 2.4 years. The mean presurgery BCVA was 0.64 ± 0.52 logarithm of the minimum angle of resolution (logMAR), and the final postsurgery BCVA was 0.61 ± 0.67 logMAR (P = 0.57). Significant improvement in the postsurgery BCVA was observed only in eyes with preserved foveal EZ (grade 3) (P < 0.01). In 62 eyes of 45 patients who underwent the HFA 10-2 test, the mean values of deviation, macular sensitivity, and foveal sensitivity at the final visit were significantly decreased compared with preoperative values (P < 0.01), whereas those in grade 3 eyes did not change significantly after the surgery (P = 0.13).CONCLUSIONS:
In the long-term course after cataract surgery in patients with RP, many patients experienced vision loss with progression of the disease. The preoperative finding of preserved foveal EZ was associated with a better visual prognosis, suggesting that EZ evaluation is useful for predicting the long-term visual outcome of cataract surgery in patients with RP.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cataract
/
Retinitis Pigmentosa
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ophthalmol Retina
Year:
2022
Document type:
Article
Affiliation country:
Japan