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MicroRNA-16 Restores Sensitivity to Tyrosine Kinase Inhibitors and Outperforms MEK Inhibitors in KRAS-Mutated Non-Small Cell Lung Cancer.
Fanini, Francesca; Bandini, Erika; Plousiou, Meropi; Carloni, Silvia; Wise, Petra; Neviani, Paolo; Murtadha, Mariam; Foca, Flavia; Fabbri, Francesco; Vannini, Ivan; Fabbri, Muller.
Affiliation
  • Fanini F; Immuno-Gene Therapy Factory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Bandini E; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Plousiou M; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Carloni S; Immuno-Gene Therapy Factory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Wise P; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
  • Neviani P; Extracellular Vesicle Core, The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
  • Murtadha M; Judy and Bernard Briskin Center for Multiple Myeloma Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Monrovia, CA 91016, USA.
  • Foca F; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Fabbri F; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Vannini I; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", 47014 Meldola, Italy.
  • Fabbri M; Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20010, USA.
Int J Mol Sci ; 22(24)2021 Dec 12.
Article in En | MEDLINE | ID: mdl-34948154
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Neoplasm / Proto-Oncogene Proteins p21(ras) / Carcinoma, Non-Small-Cell Lung / Drug Resistance, Neoplasm / MAP Kinase Kinase Kinases / MicroRNAs / Protein Kinase Inhibitors / Lung Neoplasms / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Italy Country of publication: Switzerland
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Neoplasm / Proto-Oncogene Proteins p21(ras) / Carcinoma, Non-Small-Cell Lung / Drug Resistance, Neoplasm / MAP Kinase Kinase Kinases / MicroRNAs / Protein Kinase Inhibitors / Lung Neoplasms / Mutation Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Int J Mol Sci Year: 2021 Document type: Article Affiliation country: Italy Country of publication: Switzerland