Conformal radiotherapy in management of soft tissue sarcoma in adults.
Cancer Radiother
; 26(1-2): 377-387, 2022.
Article
in En
| MEDLINE
| ID: mdl-34961656
ABSTRACT
We present the update of the recommendations of the French society of radiation oncology on soft tissue sarcomas. Currently, the initial management of sarcomas is very important as it may impact on patients' quality of life, especially in limb soft tissue sarcomas, and on overall survival in trunk sarcomas. Radiotherapy has to be discussed within a multidisciplinary board meeting with results of biopsy, eventually reexamined by a dedicated sarcoma pathologist. The role of radiotherapy varies according to localization of soft tissue sarcoma. It is part of the standard treatment in grade 2 and 3 sarcomas of the extremities and superficial trunk>5cm. In case of R1 or R2 resection, reexcision should be discussed. In such cases, it may be delivered preoperatively (50Gy/25 fractions of 2Gy) or postoperatively. In retroperitoneal sarcomas, preoperative conformal radiotherapy with or without modulated intensity cannot be proposed systematically in daily practice. Concomitant chemoradiotherapy cannot be considered a standard treatment. Intensity-modulated radiotherapy has become widely available. Other soft tissue sarcoma sites such as trunk, head and neck and gynaecological soft tissue sarcomas will be addressed, as well as other techniques that may be used such as brachytherapy and proton therapy.
Key words
Brachytherapy; Conformal radiotherapy with or without modulated intensity; Curiethérapie; French society for radiation oncology; Guidelines; Postoperative radiotherapy; Preoperative radiotherapy; Proton therapy; Protonthérapie; Radiothérapie conformationnelle avec ou sans modulation d'intensité; Radiothérapie postopératoire; Radiothérapie préopératoire; Recommandations; Sarcomes des tissus mous; Société française de radiothérapie oncologique; Soft tissue sarcoma
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sarcoma
/
Soft Tissue Neoplasms
/
Radiotherapy, Conformal
Type of study:
Etiology_studies
/
Guideline
/
Prognostic_studies
Aspects:
Patient_preference
Limits:
Adult
/
Female
/
Humans
Country/Region as subject:
Europa
Language:
En
Journal:
Cancer Radiother
Journal subject:
NEOPLASIAS
/
RADIOTERAPIA
Year:
2022
Document type:
Article