Arborinine suppresses ovarian cancer development through inhibition of LSD1.

Li, Nan; Yang, Liang; Zuo, Hongling

Li, Nan; Yang, Liang; Zuo, Hongling.

Affiliation

Li N; Department of Gynecology, the Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China. Electronic address: linan@hb2h.com.
Yang L; Department of Neurosurgery, the Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China. Electronic address: yangliang@hb2h.com.
Zuo H; Department of Gynecology, the Second Hospital of Hebei Medical University, No.215 Heping West Road, Shijiazhuang 050000, Hebei, China.

Life Sci ; 291: 120275, 2022 Feb 15.

Article in En | MEDLINE | ID: mdl-34979197

Subject(s)

Acridines/pharmacology; Carcinoma, Ovarian Epithelial/drug therapy; Histone Demethylases/metabolism; Acridines/metabolism; Animals; Antineoplastic Agents/pharmacology; Carcinoma, Ovarian Epithelial/metabolism; Carcinoma, Ovarian Epithelial/pathology; Cell Line, Tumor; Cell Movement/drug effects; Cell Proliferation/drug effects; China; Cisplatin/pharmacology; Epithelial-Mesenchymal Transition/drug effects; Female; Histone Demethylases/drug effects; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness/pathology; Ovarian Neoplasms/drug therapy; Ovarian Neoplasms/pathology; Ovary/metabolism; Paclitaxel/pharmacology; Xenograft Model Antitumor Assays

Key words

Arborinine; EMT; LSD1; Ovarian cancer; SKOV3

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acridines / Histone Demethylases / Carcinoma, Ovarian Epithelial Type of study: Prognostic_studies Limits: Animals / Female / Humans Country/Region as subject: Asia Language: En Journal: Life Sci Year: 2022 Document type: Article Country of publication: Netherlands

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