Submucosal resection via a transanal approach for treatment of epithelial rectal tumors - a multicenter study.
Vet Surg
; 51(3): 397-408, 2022 Apr.
Article
in En
| MEDLINE
| ID: mdl-34997760
ABSTRACT
OBJECTIVE:
To report complications and long-term outcomes after submucosal resections of benign and malignant epithelial rectal masses. STUDYDESIGN:
Retrospective multicentric study. SAMPLE POPULATION Medical records of 93 dogs at 7 referral hospitals.METHODS:
Records were reviewed for surgical time, diagnosis, margins, complications, and recurrences. Survival of dogs was evaluated based on tumor types, categorized as benign, carcinoma in situ, and carcinoma. The Kaplan-Meier survival curve and Cox proportional hazards analysis were used to determine the association of a range of variables with recurrence and survival time.RESULTS:
Duration of follow up was 708 days (range, 25-4383). Twenty-seven dogs (29%) developed complications. Recurrence was identified in 20/93 (21%), with 12/20 recurrent masses treated with repeat submucosal resection. Median survival was not reached in any group. The 1-,2-, 5-year survival rates for carcinomas were 95%, 89%, and 73% respectively. However, overall survival was longer for benign tumors than carcinomas (P = .001). Recurrence was more likely when complications (P = .032) or incomplete margins (P = .023) were present. Recurrence was associated with an increased risk of death (P = .046).CONCLUSION:
Submucosal resection of both benign and malignant rectal masses was associated with a low rate of severe complications and prolonged survival in the 93 dogs described here. CLINICALSIGNIFICANCE:
Submucosal resection is a suitable technique for resection of selected rectal masses.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Rectal Neoplasms
/
Carcinoma
/
Dog Diseases
/
Neoplasm Recurrence, Local
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Animals
Language:
En
Journal:
Vet Surg
Year:
2022
Document type:
Article
Affiliation country:
United kingdom