Procedural analgesia with nitrous oxide at home for epidermolysis bullosa: A case report.
Medicine (Baltimore)
; 101(1): e28474, 2022 Jan 07.
Article
in En
| MEDLINE
| ID: mdl-35029895
ABSTRACT
RATIONALE Epidermolysis bullosa (EB) is an inherited disease characterized by fragile skin with painful blistering, which requires lifelong skin and wound care. This case report describes the use of inhaled nitrous oxide (N2O) for procedural pain control at home during wound care in a young man with severe dystrophic EB. To our knowledge, only 1 case was reported by Ingelmo et al in 2017 regarding the use of N2O at home in a 4-year-old-child. To date, no such attempt has been made in adult patients. PATIENT CONCERNS Our patient was a 28-year-old man. Frequent blisters appear spontaneously, and are often preceded by erythema and itching. Patient required daily treatment daily consisting of lancing blisters with a needle and emptying them by compression. DIAGNOSES Severe recessive dystrophic EB diagnosed at the time of delivery. INTERVENTIONS:
Procedural pain control was managed by the auto-administration of an inhaled N2O and air gas mixture.OUTCOMES:
Conscious sedation with N2O leads to beneficial effects, such as reduction in dressing duration, acute procedural pain, local antibiotic needing, medication memory, anxiety, anticipatory pain, and fatigue after the dressing session. LESSONS N2O analgesia is safe and effective, resulting in a significant reduction in procedural pain and an improvement in the quality of life of patients and their caregivers.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Epidermolysis Bullosa Dystrophica
/
Epidermolysis Bullosa
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Anesthetics, Inhalation
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Pain Management
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Pain, Procedural
/
Analgesia
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Nitrous Oxide
Type of study:
Etiology_studies
Aspects:
Patient_preference
Limits:
Adult
/
Humans
/
Male
Language:
En
Journal:
Medicine (Baltimore)
Year:
2022
Document type:
Article
Affiliation country:
Italy