Your browser doesn't support javascript.
loading
Novel Oppositional Defiant Disorder 12 Months After Traumatic Brain Injury in Children and Adolescents.
Lowet, Daniel S; Vaida, Florin; Hesselink, John R; Levin, Harvey S; Ewing-Cobbs, Linda; Schachar, Russell J; Chapman, Sandra B; Bigler, Erin D; Wilde, Elisabeth A; Saunders, Ann E; Yang, Tony T; Tymofiyeva, Olga; Max, Jeffrey E.
Affiliation
  • Lowet DS; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Vaida F; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Hesselink JR; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Levin HS; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Ewing-Cobbs L; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Schachar RJ; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Chapman SB; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Bigler ED; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Wilde EA; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Saunders AE; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Yang TT; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Tymofiyeva O; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
  • Max JE; Department of Psychiatry, University of California, San Diego (Lowet, Max), Herbert Wertheim School of Public Health, Division of Biostatistics and Bioinformatics, University of California, San Diego (Vaida); Department of Radiology, University of California, San Diego (Hesselink); Department of Phy
J Neuropsychiatry Clin Neurosci ; 34(2): 149-157, 2022.
Article in En | MEDLINE | ID: mdl-35040660
ABSTRACT

OBJECTIVE:

The investigators examined the factors predictive of novel oppositional defiant disorder in the 6-12 months following traumatic brain injury (TBI).

METHODS:

Children ages 5-14 years old who experienced a TBI were recruited from consecutive admissions to five hospitals. Participants were evaluated soon after injury (baseline) for preinjury characteristics, including psychiatric disorders, adaptive function, family function, psychosocial adversity, family psychiatric history, socioeconomic status, and injury severity, to develop a biopsychosocial predictive model for development of novel oppositional defiant disorder. MRI analyses were conducted to examine potential brain lesions. Psychiatric outcome, including that of novel oppositional defiant disorder, was assessed 12 months after injury.

RESULTS:

Although 177 children were recruited for the study, 120 children without preinjury oppositional defiant disorder, conduct disorder, or disruptive behavior disorder not otherwise specified (DBD NOS) returned for the 12-month assessment. Of these 120 children, seven (5.8%) exhibited novel oppositional defiant disorder, and none developed conduct disorder or DBD NOS in the 6-12 months postinjury. Novel oppositional defiant disorder was significantly associated with lower socioeconomic status, higher psychosocial adversity, and lower preinjury adaptive functioning.

CONCLUSIONS:

These results demonstrate that novel oppositional defiant disorder following TBI selectively and negatively affects an identifiable group of children. Both proximal (preinjury adaptive function) and distal (socioeconomic status and psychosocial adversity) psychosocial variables significantly increase risk for this outcome.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit and Disruptive Behavior Disorders / Brain Injuries, Traumatic Type of study: Etiology_studies / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Humans Language: En Journal: J Neuropsychiatry Clin Neurosci Journal subject: NEUROLOGIA / PSIQUIATRIA Year: 2022 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Attention Deficit and Disruptive Behavior Disorders / Brain Injuries, Traumatic Type of study: Etiology_studies / Prognostic_studies Limits: Adolescent / Child / Child, preschool / Humans Language: En Journal: J Neuropsychiatry Clin Neurosci Journal subject: NEUROLOGIA / PSIQUIATRIA Year: 2022 Document type: Article