Assembling anisotropic colloids using curvature-mediated lipid sorting.
Soft Matter
; 18(9): 1757-1766, 2022 Mar 02.
Article
in En
| MEDLINE
| ID: mdl-35072193
The use of colloid supported lipid bilayers (CSLBs) for assembling colloidal structures has been of recent interest. Here, we use multi-component lipid bilayer membranes formed around anisotropic colloids and show that the curvature anisotropy of the colloids drives a sorting of the lipids in the membrane along the colloids. We then exploit this curvature-sensitive lipid sorting to create "shape-anisotropic patchy colloids" - specifically, we use colloids with six rods sticking out of a central cubic core, "hexapods", for this purpose and demonstrate that membrane patches self-assemble at the tip of each of the six colloidal rods. The membrane patches are rendered sticky using biotinylated lipids in complement with a biotin-binding streptavidin protein. Finally, using these "shape-anisotropic patchy colloids", we demonstrate the directed assembly of colloidal links, paving the way for the creation of heterogeneous and flexible colloidal structures.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Colloids
/
Lipid Bilayers
Language:
En
Journal:
Soft Matter
Year:
2022
Document type:
Article
Affiliation country:
India
Country of publication:
United kingdom