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Mechanistic understanding of metal-catalyzed oxidation of polysorbate 80 and monoclonal antibody in biotherapeutic formulations.
Bensaid, Fethi; Dagallier, Camille; Authelin, Jean-René; Audat, Héloïse; Filipe, Vasco; Narradon, Christine; Guibal, Pierre; Clavier, Séverine; Wils, Pierre.
Affiliation
  • Bensaid F; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France. Electronic address: fethi.bensaid@sanofi.com.
  • Dagallier C; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Authelin JR; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Audat H; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Filipe V; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Narradon C; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Guibal P; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Clavier S; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
  • Wils P; Sanofi-Aventis Research and Development, 1 impasse des ateliers, 94403 Vitry-Sur-Seine, France.
Int J Pharm ; 615: 121496, 2022 Mar 05.
Article in En | MEDLINE | ID: mdl-35074436
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Antibodies, Monoclonal Language: En Journal: Int J Pharm Year: 2022 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polysorbates / Antibodies, Monoclonal Language: En Journal: Int J Pharm Year: 2022 Document type: Article Country of publication: Netherlands