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P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss.
Stefanski, Heather E; Xing, Yan; Nicholls, Jemma; Jonart, Leslie; Goren, Emily; Taylor, Patricia A; Mills, Alea A; Riddle, Megan; McGrath, John; Tolar, Jakub; Hollander, Georg A; Blazar, Bruce R.
Affiliation
  • Stefanski HE; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Xing Y; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Nicholls J; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Jonart L; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Goren E; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Taylor PA; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Mills AA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, New York, United States of America.
  • Riddle M; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • McGrath J; Molecular Dermatology, St John's Institute of Dermatology, King's College, London, England.
  • Tolar J; Division of Blood and Marrow Transplantation, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States of America.
  • Hollander GA; Department of Paediatrics, University of Oxford, Oxford, United Kingdom.
  • Blazar BR; Department of Biomedicine, Basel University Children's Hospital, University of Basel, Basel, Switzerland.
PLoS One ; 17(1): e0261770, 2022.
Article in En | MEDLINE | ID: mdl-35077450
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymus Gland / Trans-Activators / Promoter Regions, Genetic / Gene Deletion / Alopecia / Forkhead Transcription Factors / Gene Knockout Techniques Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thymus Gland / Trans-Activators / Promoter Regions, Genetic / Gene Deletion / Alopecia / Forkhead Transcription Factors / Gene Knockout Techniques Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: United States