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Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.
DiCorpo, Daniel; LeClair, Jessica; Cole, Joanne B; Sarnowski, Chloé; Ahmadizar, Fariba; Bielak, Lawrence F; Blokstra, Anneke; Bottinger, Erwin P; Chaker, Layal; Chen, Yii-Der I; Chen, Ye; de Vries, Paul S; Faquih, Tariq; Ghanbari, Mohsen; Gudmundsdottir, Valborg; Guo, Xiuqing; Hasbani, Natalie R; Ibi, Dorina; Ikram, M Arfan; Kavousi, Maryam; Leonard, Hampton L; Leong, Aaron; Mercader, Josep M; Morrison, Alanna C; Nadkarni, Girish N; Nalls, Mike A; Noordam, Raymond; Preuss, Michael; Smith, Jennifer A; Trompet, Stella; Vissink, Petra; Yao, Jie; Zhao, Wei; Boerwinkle, Eric; Goodarzi, Mark O; Gudnason, Vilmundur; Jukema, J Wouter; Kardia, Sharon L R; Loos, Ruth J F; Liu, Ching-Ti; Manning, Alisa K; Mook-Kanamori, Dennis; Pankow, James S; Picavet, H Susan J; Sattar, Naveed; Simonsick, Eleanor M; Verschuren, W M Monique; Willems van Dijk, Ko; Florez, Jose C; Rotter, Jerome I.
Affiliation
  • DiCorpo D; Department of Biostatistics, Boston University School of Public Health, Boston, MA.
  • LeClair J; Department of Biostatistics, Boston University School of Public Health, Boston, MA.
  • Cole JB; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.
  • Sarnowski C; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Ahmadizar F; Division of Endocrinology, Boston Children's Hospital, Boston, MA.
  • Bielak LF; Department of Biostatistics, Boston University School of Public Health, Boston, MA.
  • Blokstra A; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Bottinger EP; Julius Global Health, University Utrecht Medical Center, Utrecht, the Netherlands.
  • Chaker L; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI.
  • Chen YI; National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
  • Chen Y; Hasso Plattner Institute Digital Health, Potsdam, Germany.
  • de Vries PS; Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Faquih T; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Ghanbari M; Department of Internal Medicine, Division of Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands.
  • Gudmundsdottir V; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
  • Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA.
  • Hasbani NR; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA.
  • Ibi D; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX.
  • Ikram MA; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
  • Kavousi M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Leonard HL; Icelandic Heart Association, Kopavogur, Iceland.
  • Leong A; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
  • Mercader JM; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA.
  • Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX.
  • Nadkarni GN; National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
  • Nalls MA; Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands.
  • Noordam R; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Preuss M; Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
  • Smith JA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD.
  • Trompet S; Data Tecnica International, Glen Echo, MD.
  • Vissink P; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD.
  • Yao J; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.
  • Zhao W; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Boerwinkle E; Department of Medicine, Harvard Medical School, Boston, MA.
  • Goodarzi MO; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA.
  • Gudnason V; Programs in Metabolism and Medical & Population Genetics, Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA.
  • Jukema JW; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA.
  • Kardia SLR; Department of Medicine, Harvard Medical School, Boston, MA.
  • Loos RJF; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA.
  • Liu CT; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Manning AK; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Mook-Kanamori D; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD.
  • Pankow JS; Data Tecnica International, Glen Echo, MD.
  • Picavet HSJ; Center for Alzheimer's and Related Dementias, National Institutes of Health, Bethesda, MD.
  • Sattar N; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Simonsick EM; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
  • Verschuren WMM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI.
  • Willems van Dijk K; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI.
  • Florez JC; Section of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, the Netherlands.
  • Rotter JI; National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Diabetes Care ; 45(3): 674-683, 2022 03 01.
Article in En | MEDLINE | ID: mdl-35085396
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Diabetes Mellitus, Type 2 Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Diabetes Care Year: 2022 Document type: Article Affiliation country: Morocco
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Diabetes Mellitus, Type 2 Type of study: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspects: Patient_preference Limits: Humans Language: En Journal: Diabetes Care Year: 2022 Document type: Article Affiliation country: Morocco