Pre-clinical and clinical studies on the role of RBM3 in muscle-invasive bladder cancer: longitudinal expression, transcriptome-level effects and modulation of chemosensitivity.

Wahlin, Sara; Boman, Karolina; Moran, Bruce; Nodin, Björn; Gallagher, William M; Karnevi, Emelie; Jirström, Karin

Wahlin, Sara; Boman, Karolina; Moran, Bruce; Nodin, Björn; Gallagher, William M; Karnevi, Emelie; Jirström, Karin.

Affiliation

Wahlin S; Division of Oncology and Therapeutic Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden. Sara.wahlin@med.lu.se.
Boman K; Division of Oncology and Therapeutic Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Moran B; UCD School of Biomolecular and Biomedical Sciences, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
Nodin B; Division of Oncology and Therapeutic Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Gallagher WM; UCD School of Biomolecular and Biomedical Sciences, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
Karnevi E; Division of Oncology and Therapeutic Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.
Jirström K; Division of Oncology and Therapeutic Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.

BMC Cancer ; 22(1): 131, 2022 Feb 02.

Article in En | MEDLINE | ID: mdl-35109796

Subject(s)

Biomarkers, Tumor/metabolism; Drug Resistance, Neoplasm/drug effects; RNA-Binding Proteins/metabolism; Urinary Bladder Neoplasms/pathology; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor/genetics; Cell Line, Tumor; Cisplatin/therapeutic use; Cohort Studies; Deoxycytidine/analogs & derivatives; Deoxycytidine/therapeutic use; Female; Gene Expression Profiling; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoadjuvant Therapy; RNA-Binding Proteins/genetics; Resting Phase, Cell Cycle; Survival Analysis; Sweden; Urinary Bladder Neoplasms/metabolism; Urinary Bladder Neoplasms/mortality; Urinary Bladder Neoplasms/therapy; Gemcitabine

Key words

Biomarker; Cell cycle; Chemotherapy response; Muscle-invasive bladder cancer; Prediction; RBM3

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Biomarkers, Tumor / RNA-Binding Proteins / Drug Resistance, Neoplasm Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: BMC Cancer Journal subject: NEOPLASIAS Year: 2022 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

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