Development and Validation of Stability-Indicating Assay Method for a Novel Oxazolidinone (PH-192) with Anticonvulsant Activity by Using UHPLC-QToF-MS.

Al-Tannak, Naser F; Phillips, Oludotun A; Kamal, Husein J; Hemdan, Ahmed

Al-Tannak, Naser F; Phillips, Oludotun A; Kamal, Husein J; Hemdan, Ahmed.

Affiliation

Al-Tannak NF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.
Phillips OA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.
Kamal HJ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait.
Hemdan A; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G1 1XQ, UK.

Molecules ; 27(3)2022 Feb 06.

Article in En | MEDLINE | ID: mdl-35164353

Subject(s)

Anticonvulsants/chemistry; Anticonvulsants/pharmacology; Chromatography, High Pressure Liquid/methods; Oxazolidinones/chemistry; Oxazolidinones/pharmacology; Seizures/drug therapy; Tandem Mass Spectrometry/methods; Chromatography, Liquid; Humans; Limit of Detection

Key words

GC-MS; PH-189; UPLC; antimycobacterial activity; linezolid; substituted-glycinyl triazolyl-oxazolidinone

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures / Chromatography, High Pressure Liquid / Oxazolidinones / Tandem Mass Spectrometry / Anticonvulsants Limits: Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2022 Document type: Article Affiliation country: Kuwait Country of publication: Switzerland

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