Adipose Mitochondrial Complex I Deficiency Modulates Inflammation and Glucose Homeostasis in a Sex-Dependent Manner.

Choi, Kyung-Mi; Ryan, Karen K; Yoon, John C

Choi, Kyung-Mi; Ryan, Karen K; Yoon, John C.

Affiliation

Choi KM; Division of Endocrinology, Department of Internal Medicine, University of California Davis School of Medicine, Davis, CA 95616, USA.
Ryan KK; Department of Neurobiology, Physiology, and Behavior, College of Biological Sciences, University of California Davis, Davis, CA 95616, USA.
Yoon JC; Division of Endocrinology, Department of Internal Medicine, University of California Davis School of Medicine, Davis, CA 95616, USA.

Endocrinology ; 163(4)2022 04 01.

Article in En | MEDLINE | ID: mdl-35171275

Subject(s)

Diabetes Mellitus, Type 2; Adipose Tissue, Brown/metabolism; Animals; Diabetes Mellitus, Type 2/metabolism; Electron Transport Complex I/deficiency; Electron Transport Complex I/genetics; Electron Transport Complex I/metabolism; Female; Glucose/metabolism; Homeostasis/genetics; Inflammation/genetics; Inflammation/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Diseases; Thermogenesis/genetics

Key words

FGF21; Ndufs4; impaired glucose tolerance; inflammation; mitochondria

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 Limits: Animals Language: En Journal: Endocrinology Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States

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