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A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells.
Shen, Jia Z; Qiu, Zhixin; Wu, Qiulian; Zhang, Guoxin; Harris, Rebecca; Sun, Dahui; Rantala, Juha; Barshop, William D; Zhao, Linjie; Lv, Deguan; Won, Kwang-Ai; Wohlschlegel, James; Sangfelt, Olle; Laman, Heike; Rich, Jeremy N; Spruck, Charles.
Affiliation
  • Shen JZ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Qiu Z; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Wu Q; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Zhang G; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, CA 92037, USA.
  • Harris R; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
  • Sun D; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Rantala J; Misvik Biology Ltd., 20520 Turku, Finland.
  • Barshop WD; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Zhao L; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Lv D; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15213, USA.
  • Won KA; KBiohub, Moraga, CA 94556, USA.
  • Wohlschlegel J; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Sangfelt O; Department of Cell and Molecular Biology, Karolinska Institute, Stockholm 171 77, Sweden.
  • Laman H; Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
  • Rich JN; University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA 15213, USA; Division of Regenerative Medicine, Department of Medicine, University of California, San Diego, CA 92037, USA; Department of Neurology, University of Pittsburgh, Pittsburgh, PA 15213, USA. Electronic address: d
  • Spruck C; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA. Electronic address: cspruck@sbpdiscovery.org.
Mol Cell ; 82(6): 1123-1139.e8, 2022 03 17.
Article in En | MEDLINE | ID: mdl-35182481
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: F-Box Proteins / F-Box-WD Repeat-Containing Protein 7 / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: F-Box Proteins / F-Box-WD Repeat-Containing Protein 7 / Neoplasms Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States