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A novel next-generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys.
Lauritzen, Brian; Bjelke, Mads; Björkdahl, Olle; Bloem, Esther; Keane, Kevin; Kjalke, Marianne; Rossen, Marie; Lippert, Solvej Lund; Weldingh, Karin Nana; Skydsgaard, Mikala; Kjellev, Stine.
Affiliation
  • Lauritzen B; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Bjelke M; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Björkdahl O; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Bloem E; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Keane K; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Kjalke M; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Rossen M; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Lippert SL; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Weldingh KN; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Skydsgaard M; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
  • Kjellev S; Global Drug Discovery, Novo Nordisk A/S, Måløv, Denmark.
J Thromb Haemost ; 20(6): 1312-1324, 2022 06.
Article in En | MEDLINE | ID: mdl-35191180
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Hemophilia A Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2022 Document type: Article Affiliation country: Denmark Country of publication: United kingdom
Fulltext
Add to My VHL
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XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombosis / Hemophilia A Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Thromb Haemost Journal subject: HEMATOLOGIA Year: 2022 Document type: Article Affiliation country: Denmark Country of publication: United kingdom