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2-Deoxy-d-glucose induces deglycosylation of proinflammatory cytokine receptors and strongly reduces immunological responses in mouse models of inflammation.
Uehara, Ikuno; Kajita, Mitsuko; Tanimura, Atsuko; Hida, Shigeaki; Onda, Munehiko; Naito, Zenya; Taki, Shinsuke; Tanaka, Nobuyuki.
Affiliation
  • Uehara I; Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
  • Kajita M; Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
  • Tanimura A; Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
  • Hida S; Department of Molecular and Cellular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Japan.
  • Onda M; Department of Pathology, Integrative Oncological Pathology, Nippon Medical School, Tokyo, Japan.
  • Naito Z; Department of Pathology, Integrative Oncological Pathology, Nippon Medical School, Tokyo, Japan.
  • Taki S; Department of Molecular and Cellular Immunology, Shinshu University School of Medicine, Matsumoto, Japan.
  • Tanaka N; Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, Tokyo, Japan.
Pharmacol Res Perspect ; 10(2): e00940, 2022 04.
Article in En | MEDLINE | ID: mdl-35212163
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycosylation / Anti-Inflammatory Agents, Non-Steroidal / Receptors, Cytokine / Deoxyglucose / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharmacol Res Perspect Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycosylation / Anti-Inflammatory Agents, Non-Steroidal / Receptors, Cytokine / Deoxyglucose / Inflammation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharmacol Res Perspect Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United States