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Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).
Shi, Yuan; Cui, Mochen; Ochs, Katharina; Brendel, Matthias; Strübing, Felix L; Briel, Nils; Eckenweber, Florian; Zou, Chengyu; Banati, Richard B; Liu, Guo-Jun; Middleton, Ryan J; Rupprecht, Rainer; Rudolph, Uwe; Zeilhofer, Hanns Ulrich; Rammes, Gerhard; Herms, Jochen; Dorostkar, Mario M.
Affiliation
  • Shi Y; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Cui M; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Ochs K; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
  • Brendel M; Munich Medical Research School, Ludwig Maximilian University of Munich, Munich, Germany.
  • Strübing FL; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Briel N; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Eckenweber F; Munich Medical Research School, Ludwig Maximilian University of Munich, Munich, Germany.
  • Zou C; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Banati RB; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Liu GJ; Department of Nuclear Medicine, University Hospital of Munich, Ludwig Maximilian University of Munich, Munich, Germany.
  • Middleton RJ; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Rupprecht R; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Rudolph U; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Zeilhofer HU; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
  • Rammes G; Munich Medical Research School, Ludwig Maximilian University of Munich, Munich, Germany.
  • Herms J; Department of Nuclear Medicine, University Hospital of Munich, Ludwig Maximilian University of Munich, Munich, Germany.
  • Dorostkar MM; Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
Nat Neurosci ; 25(3): 317-329, 2022 03.
Article in En | MEDLINE | ID: mdl-35228700
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, GABA / Microglia / Diazepam Limits: Animals Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, GABA / Microglia / Diazepam Limits: Animals Language: En Journal: Nat Neurosci Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United States