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Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling.
Gomez-Soler, Maricel; Gehring, Marina P; Lechtenberg, Bernhard C; Zapata-Mercado, Elmer; Ruelos, Alyssa; Matsumoto, Mike W; Hristova, Kalina; Pasquale, Elena B.
Affiliation
  • Gomez-Soler M; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Gehring MP; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Lechtenberg BC; Ubiquitin Signalling Division, The Walter and Eliza Hall Institute of Medical Research, Parkville Victoria 3052, Australia and Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Zapata-Mercado E; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Ruelos A; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Matsumoto MW; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
  • Hristova K; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Pasquale EB; Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA.
iScience ; 25(3): 103870, 2022 Mar 18.
Article in En | MEDLINE | ID: mdl-35243233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: IScience Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: IScience Year: 2022 Document type: Article Affiliation country: United States