Effect of dentifrices with different pH and fluoride concentrations on fluoride levels in biofilm and nails: an RCT.
Braz Oral Res
; 36: e043, 2022.
Article
in En
| MEDLINE
| ID: mdl-35293508
ABSTRACT
PURPOSE:
to evaluate the effect of dentifrice pH and fluoride concentration ([F]) on fluoride uptake on the biofilm and nails of children from a non-fluoridated area.METHODS:
two hundred and twenty-eight two- to four-year-old children were randomly allocated into 3 groups according to the type of dentifrice G1 1100 µg F/g, pH 4.5 (n = 76); G2 750 µg F/g, pH 4.5 (n = 74); and G3 1100 µg F/g, pH 7.0 (n = 78). Nails were collected at 4, 8, and 12 months after starting dentifrice use and biofilm was collected 5 and 60 minutes after toothbrushing. The concentrations of F in nails and biofilm were analyzed by HMDS facilitated diffusion. Data were analyzed by Kruskal-Wallis/Mann-Whitney's test and the comparison between biofilm collection times was done using Wilcoxon test (p £ 0.05).RESULTS:
a significant reduction of [F] in biofilm was observed 60 minutes after toothbrushing, regardless of the dentifrice used. However, 5 minutes after toothbrushing, G1 had a significantly higher [F] compared to G2 and G3, and 60 minutes after toothbrushing, [F] was significantly higher for G1 and G2 compared to G3. G1 and G3 had significantly higher [F] in the nails compared to G2.CONCLUSION:
a lower dentifrice concentration is a relevant factor for the reduction of excessive fluoride intake. The use of a low-F acidified dentifrice combines the reduction of fluoride uptake with caries prevention by leading to greater incorporation of F into the biofilm over time.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Dentifrices
/
Fluorides
Type of study:
Clinical_trials
Limits:
Child
/
Child, preschool
/
Humans
Language:
En
Journal:
Braz Oral Res
Journal subject:
ODONTOLOGIA
Year:
2022
Document type:
Article
Affiliation country:
Brazil