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Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Nguyen-Tu, Marie-Sophie; Harris, Joseph; Martinez-Sanchez, Aida; Chabosseau, Pauline; Hu, Ming; Georgiadou, Eleni; Pollard, Alice; Otero, Pablo; Lopez-Noriega, Livia; Leclerc, Isabelle; Sakamoto, Kei; Schmoll, Dieter; Smith, David M; Carling, David; Rutter, Guy A.
Affiliation
  • Nguyen-Tu MS; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Harris J; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Martinez-Sanchez A; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Chabosseau P; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Hu M; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Georgiadou E; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Pollard A; MRC- London Institute of Medical Sciences, Imperial College London, London, UK.
  • Otero P; Structure Biophysics and Fragments, Discovery Sciences, AstraZeneca R&D, Cambridge, UK.
  • Lopez-Noriega L; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Leclerc I; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Sakamoto K; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  • Schmoll D; Novo Nordisk Center for Basic Metabolic Research, Copenhagen, Denmark.
  • Smith DM; Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, Germany.
  • Carling D; Emerging Innovations Unit, Discovery Sciences, AstraZeneca R&D , Cambridge, UK.
  • Rutter GA; MRC- London Institute of Medical Sciences, Imperial College London, London, UK.
Diabetologia ; 65(6): 997-1011, 2022 06.
Article in En | MEDLINE | ID: mdl-35294578

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Diabetologia Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Insulin-Secreting Cells Limits: Animals Language: En Journal: Diabetologia Year: 2022 Document type: Article Affiliation country: United kingdom Country of publication: Germany