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Uncontrolled mitochondrial calcium uptake underlies the pathogenesis of neurodegeneration in MICU1-deficient mice and patients.
Singh, Raghavendra; Bartok, Adam; Paillard, Melanie; Tyburski, Ashley; Elliott, Melanie; Hajnóczky, György.
Affiliation
  • Singh R; MitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Bartok A; MitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Paillard M; Departent of Biochemistry, Semmelweis University, Budapest, Hungary.
  • Tyburski A; MitoCare Center, Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Elliott M; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
  • Hajnóczky G; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Sci Adv ; 8(11): eabj4716, 2022 03 18.
Article in En | MEDLINE | ID: mdl-35302860
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Cation Transport Proteins / Mitochondrial Membrane Transport Proteins Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Adv Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neurodegenerative Diseases / Cation Transport Proteins / Mitochondrial Membrane Transport Proteins Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Adv Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States