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CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata.
Ceballos-Garzon, Andres; Roman, Elvira; Pla, Jesús; Pagniez, Fabrice; Amado, Daniela; Alméciga-Díaz, Carlos J; Le Pape, Patrice; Parra-Giraldo, Claudia M.
Affiliation
  • Ceballos-Garzon A; Unidad de Proteómica y Micosis Humanas, Grupo de Enfermedades Infecciosas, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
  • Roman E; Department of Parasitology and Medical Mycology, Faculty of Pharmacy, University of Nantes, Nantes, France.
  • Pla J; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Universidad Complutense de Madrid, Madrid, Spain.
  • Pagniez F; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Universidad Complutense de Madrid, Madrid, Spain.
  • Amado D; Department of Parasitology and Medical Mycology, Faculty of Pharmacy, University of Nantes, Nantes, France.
  • Alméciga-Díaz CJ; Unidad de Proteómica y Micosis Humanas, Grupo de Enfermedades Infecciosas, Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
  • Le Pape P; Institute for the Study of Inborn Errors of Metabolism, Faculty of Science, Pontificia Universidad Javeriana, Bogotá, D.C., Colombia.
  • Parra-Giraldo CM; Department of Parasitology and Medical Mycology, Faculty of Pharmacy, University of Nantes, Nantes, France.
PLoS One ; 17(3): e0265777, 2022.
Article in En | MEDLINE | ID: mdl-35303047
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida glabrata / Echinocandins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Colombia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Candida glabrata / Echinocandins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2022 Document type: Article Affiliation country: Colombia