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A tandem-repeat dimeric RBD protein-based covid-19 vaccine zf2001 protects mice and nonhuman primates.
An, Yaling; Li, Shihua; Jin, Xiyue; Han, Jian-Bao; Xu, Kun; Xu, Senyu; Han, Yuxuan; Liu, Chuanyu; Zheng, Tianyi; Liu, Mei; Yang, Mi; Song, Tian-Zhang; Huang, Baoying; Zhao, Li; Wang, Wen; A, Ruhan; Cheng, Yingjie; Wu, Changwei; Huang, Enqi; Yang, Shilong; Wong, Gary; Bi, Yuhai; Ke, Changwen; Tan, Wenjie; Yan, Jinghua; Zheng, Yong-Tang; Dai, Lianpan; Gao, George F.
Affiliation
  • An Y; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People's Republic of China.
  • Li S; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Jin X; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Han JB; School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.
  • Xu K; Kunming National High-Level Biosafety Research Center for Non-human Primates, Center for Biosafety Mega-Science, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650107, People's Republic of China.
  • Xu S; Key Laboratory of Tropical Translational Medicine of Ministry of Education, School of Tropical Medicine and Laboratory Medicine, The First Affiliated Hospital, Hainan Medical University, Hainan, 571199, People's Republic of China.
  • Han Y; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Liu C; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Zheng T; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 101408, People's Republic of China.
  • Liu M; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Yang M; Laboratory of Animal Infectious Diseases, College of Animal Sciences and Veterinary Medicine, Guangxi University, Nanning, 530000, People's Republic of China.
  • Song TZ; Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Huang B; Zhejiang University School of Medicine, Hangzhou 310058, People's Republic of China.
  • Zhao L; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Wang W; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • A R; Key Laboratory of Animal Models and Human Disease Mechanism of the Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academic of Sciences, Kunming, 650223, People's Republic of China.
  • Cheng Y; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People's Republic of China.
  • Wu C; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People's Republic of China.
  • Huang E; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People's Republic of China.
  • Yang S; NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, People's Republic of China.
  • Wong G; Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People's Republic of China.
  • Bi Y; Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People's Republic of China.
  • Ke C; Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People's Republic of China.
  • Tan W; Anhui Zhifei Longcom Biopharmaceutical Co. Ltd, Anhui, 230088, People's Republic of China.
  • Yan J; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai 200031, People's Republic of China.
  • Zheng YT; Department of Microbiology-Infectiology and Immunology, Laval University, Quebec City G1, Canada.
  • Dai L; CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
  • Gao GF; CAS Center for Influenza Research and Early-Warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, People's Republic of China.
Emerg Microbes Infect ; 11(1): 1058-1071, 2022 Dec.
Article in En | MEDLINE | ID: mdl-35311493

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Limits: Animals / Humans Language: En Journal: Emerg Microbes Infect Year: 2022 Document type: Article Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Vaccines / COVID-19 Limits: Animals / Humans Language: En Journal: Emerg Microbes Infect Year: 2022 Document type: Article Country of publication: United States