Determination of fluoroquinolones in chicken muscle by molecularly imprinted graphitic carbon nitride-based solid-phase extraction and ultra-performance liquid chromatography.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
; 39(5): 901-911, 2022 May.
Article
in En
| MEDLINE
| ID: mdl-35312418
ABSTRACT
A graphitic carbon nitride was synthesised and nalidixic acid (NA) based molecularly imprinted microspheres (MIMs) were polymerised on its surface to create a composite material. After characterisation and evaluation of its absorption ability, the composite was used to prepare a solid-phase extraction (SPE) cartridge for purification of fluoroquinolones in chicken muscle, analysed by ultra-performance liquid chromatography. The cartridge showed high absorption capacities (378-559 µg) and high recoveries (92.1-99.4%) for eight fluoroquinolones, and could be reused at least 20 times. The limits of detection for the 8 drugs were 0.2-0.8 ng g-1, and recoveries from standard fortified blank chicken muscle samples were 71.9-96.8%. This is the first study reporting the use of molecularly imprinted graphitic carbon nitride composite to determine the residue of veterinary drug in foods of animal origin.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Fluoroquinolones
/
Molecular Imprinting
Limits:
Animals
Language:
En
Journal:
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2022
Document type:
Article
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM