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A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci.
van Bree, Elisabeth J; Guimarães, Rita L F P; Lundberg, Mischa; Blujdea, Elena R; Rosenkrantz, Jimi L; White, Fred T G; Poppinga, Josse; Ferrer-Raventós, Paula; Schneider, Anne-Fleur E; Clayton, Isabella; Haussler, David; Reinders, Marcel J T; Holstege, Henne; Ewing, Adam D; Moses, Colette; Jacobs, Frank M J.
Affiliation
  • van Bree EJ; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Guimarães RLFP; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Lundberg M; Genomics of Neurodegenerative Diseases and Aging, Department of Human Genetics, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.
  • Blujdea ER; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.
  • Rosenkrantz JL; Mater Research Institute-University of Queensland, Woolloongabba, QLD 4102, Australia.
  • White FTG; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Poppinga J; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Ferrer-Raventós P; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Schneider AE; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Clayton I; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Haussler D; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Reinders MJT; Evolutionary Neurogenomics, Swammerdam Institute for Life Sciences, University of Amsterdam, 1098 XH Amsterdam, The Netherlands.
  • Holstege H; UC Santa Cruz Genomics Institute, and Howard Hughes Medical Institute, UC Santa Cruz, Santa Cruz, California 95064, USA.
  • Ewing AD; Delft Bioinformatics Lab, Delft University of Technology, 2628 XE Delft, The Netherlands.
  • Moses C; Genomics of Neurodegenerative Diseases and Aging, Department of Human Genetics, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.
  • Jacobs FMJ; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, 1081 HV Amsterdam, The Netherlands.
Genome Res ; 32(4): 656-670, 2022 04.
Article in En | MEDLINE | ID: mdl-35332097

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Transposable Elements / Genome-Wide Association Study Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Genome Res Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2022 Document type: Article Affiliation country: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Transposable Elements / Genome-Wide Association Study Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Genome Res Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2022 Document type: Article Affiliation country: Netherlands