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The Roles of MicroRNA in Pancreatic Cancer Progression.
Kt, Ramya Devi; Karthick, Dharshene; Saravanaraj, Kirtikesav Salem; Jaganathan, M K; Ghorai, Suvankar; Hemdev, Sanjana Prakash.
Affiliation
  • Kt RD; Department of Biotechnology, School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Tamil Nadu, India.
  • Karthick D; Department of Biotechnology, School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Tamil Nadu, India.
  • Saravanaraj KS; Department of Biotechnology, School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Tamil Nadu, India.
  • Jaganathan MK; Department of Biotechnology, School of Bioengineering, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Tamil Nadu, India.
  • Ghorai S; Department of Microbiology, Raiganj University, Uttar Dinajpur, India.
  • Hemdev SP; School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA, USA.
Cancer Invest ; 40(8): 700-709, 2022 Sep.
Article in En | MEDLINE | ID: mdl-35333689
ABSTRACT
Pancreatic Ductal Adenocarcinoma (PDAC) has a poor patient survival rate in comparison with other cancer types, even after targeted therapy, chemotherapy, and immunotherapy. Therefore, a great deal needs to be done to gain a better understanding of the biology and identification of prognostic and predictive markers for the development of superior therapies. The microRNAs (miRNAs) belong to small non-coding RNAs that regulate post-transcriptional gene expression. Several shreds of evidence indicate that miRNAs play an important role in the pathogenesis of pancreatic cancer. Here we review the recent developments in miRNAs and their target role in the development, metastasis, migration, and invasion.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / MicroRNAs Limits: Humans Language: En Journal: Cancer Invest Year: 2022 Document type: Article Affiliation country: India

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / MicroRNAs Limits: Humans Language: En Journal: Cancer Invest Year: 2022 Document type: Article Affiliation country: India