The Roles of MicroRNA in Pancreatic Cancer Progression.
Cancer Invest
; 40(8): 700-709, 2022 Sep.
Article
in En
| MEDLINE
| ID: mdl-35333689
ABSTRACT
Pancreatic Ductal Adenocarcinoma (PDAC) has a poor patient survival rate in comparison with other cancer types, even after targeted therapy, chemotherapy, and immunotherapy. Therefore, a great deal needs to be done to gain a better understanding of the biology and identification of prognostic and predictive markers for the development of superior therapies. The microRNAs (miRNAs) belong to small non-coding RNAs that regulate post-transcriptional gene expression. Several shreds of evidence indicate that miRNAs play an important role in the pathogenesis of pancreatic cancer. Here we review the recent developments in miRNAs and their target role in the development, metastasis, migration, and invasion.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pancreatic Neoplasms
/
MicroRNAs
Limits:
Humans
Language:
En
Journal:
Cancer Invest
Year:
2022
Document type:
Article
Affiliation country:
India