Genetic, environmental and life-style factors associated with longevity. Protocol and response of the LONGECYL Study.
Gac Sanit
; 36(3): 260-264, 2022.
Article
in En
| MEDLINE
| ID: mdl-35339311
ABSTRACT
OBJECTIVE:
To describe the objectives, the methodological approach, the response rate of the Genetic, Environmental and Life-style Factors Study in Castilla y León (Spain).METHOD:
The Health Sentinel Network studied a sample of long-lived individuals aged 95 or more (LLI). The study included biological samples processed with the Global Screening Array v3.0 that contains a total of 730,059 markers. Written consent was obtained before the examination.CONCLUSIONS:
The LLI contacted were 944, and 760 were completed studied. The 87.4% of LLI were born in Castile and Leon and only 1% were non-native of Spain. Severe cognitive impairment was declared in 8.1% of men and 19.2% of women. Genotyping was performed in 739 LLI, the 78.3% of the contacted sample. Family doctors and nurses achieve high participation in population-based studies. DNA samples were taken from 94% of fully studied LLI, and 100% of these samples where successfully genotyped.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Life Style
/
Longevity
Type of study:
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
En
Journal:
Gac Sanit
Journal subject:
SAUDE PUBLICA
Year:
2022
Document type:
Article