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Mechanistic Studies and Formulation Mitigations of Adeno-associated Virus Capsid Rupture During Freezing and Thawing: Mechanisms of Freeze/Thaw Induced AAV Rupture.
Bee, Jared S; Zhang, Yu; Finkner, Sheyla; O'Berry, Kristin; Kaushal, Akanksha; Phillippi, Megan Kuhn; DePaz, Roberto A; Webber, Keith; Marshall, Tristan.
Affiliation
  • Bee JS; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA. Electronic address: jaredsbee@gmail.com.
  • Zhang Y; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
  • Finkner S; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
  • O'Berry K; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
  • Kaushal A; Analytical Sciences, REGENXBIO Inc., Rockville, MD 20850, USA.
  • Phillippi MK; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
  • DePaz RA; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
  • Webber K; Analytical Sciences, REGENXBIO Inc., Rockville, MD 20850, USA.
  • Marshall T; Formulation and Drug Product Development, REGENXBIO Inc., Rockville, MD 20850, USA.
J Pharm Sci ; 111(7): 1868-1878, 2022 07.
Article in En | MEDLINE | ID: mdl-35351496
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capsid / Dependovirus Type of study: Risk_factors_studies Language: En Journal: J Pharm Sci Year: 2022 Document type: Article Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Capsid / Dependovirus Type of study: Risk_factors_studies Language: En Journal: J Pharm Sci Year: 2022 Document type: Article Country of publication: United States