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Neuronal C/EBPß/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression.
Xia, Yiyuan; Qadota, Hiroshi; Wang, Zhi-Hao; Liu, Pai; Liu, Xia; Ye, Karen X; Matheny, Courtney J; Berglund, Ken; Yu, Shan Ping; Drake, Derek; Bennett, David A; Wang, Xiao-Chuan; Yankner, Bruce A; Benian, Guy M; Ye, Keqiang.
Affiliation
  • Xia Y; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Qadota H; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Wang ZH; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Liu P; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Liu X; Neuroscience program, Laney Graduate School, Emory University, Atlanta, GA 30322, USA.
  • Ye KX; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Matheny CJ; Emory College of Arts and Sciences, Emory University, Atlanta, GA 30322, USA.
  • Berglund K; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.
  • Yu SP; Department of Neurosurgery, Emory University, Atlanta, GA 30322, USA.
  • Drake D; Department of Anesthesiology, Emory University, Atlanta, GA 30322, USA.
  • Bennett DA; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Wang XC; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
  • Yankner BA; Department of Pathophysiology, Key Laboratory of Ministry of Education of Neurological Diseases, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Benian GM; Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu 226001, China.
  • Ye K; Department of Genetics, Harvard Medical School, Boston, MA, USA.
Sci Adv ; 8(13): eabj8658, 2022 04.
Article in En | MEDLINE | ID: mdl-35353567
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans Proteins / Longevity Limits: Animals Language: En Journal: Sci Adv Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Caenorhabditis elegans Proteins / Longevity Limits: Animals Language: En Journal: Sci Adv Year: 2022 Document type: Article Affiliation country: United States