Formulation of Biopharmaceutical Dry Powder Inhaler Using the Void Forming Index (VFI) to Detect and Avoid Powder Caking in Dry Powder Inhaler Formulations.

Maruyama, Sunao; Miyajima, Makoto; Yonemochi, Etsuo

Maruyama, Sunao; Miyajima, Makoto; Yonemochi, Etsuo.

Affiliation

Maruyama S; Formulation Technology Research Laboratories, Daiichi Sankyo Co., Ltd.
Miyajima M; Formulation Technology Research Laboratories, Daiichi Sankyo Co., Ltd.
Yonemochi E; Department of Physical Chemistry, School of Pharmacy and Pharmaceutical Sciences, Hoshi University.

Chem Pharm Bull (Tokyo) ; 70(4): 245-253, 2022.

Article in En | MEDLINE | ID: mdl-35370200

Subject(s)

Biological Products; Dry Powder Inhalers; Administration, Inhalation; Particle Size; Powders/chemistry

Key words

dry powder inhaler; inverse gas chromatography; lysozyme; powder cohesiveness; void forming index

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Dry Powder Inhalers Language: En Journal: Chem Pharm Bull (Tokyo) Year: 2022 Document type: Article Country of publication: Japan

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