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Poly(vinyl alcohol)/Plant Extracts Films: Preparation, Surface Characterization and Antibacterial Studies against Gram Positive and Gram Negative Bacteria.
Barbalata-Mândru, Mihaela; Serbezeanu, Diana; Butnaru, Maria; Rîmbu, Cristina Mihaela; Enache, Alexandru Alin; Aflori, Magdalena.
Affiliation
  • Barbalata-Mândru M; "Petru Poni" Institute of Macromolecular Chemistry, 41A Aleea Gr. GhicaVoda, 700487 Iasi, Romania.
  • Serbezeanu D; "Petru Poni" Institute of Macromolecular Chemistry, 41A Aleea Gr. GhicaVoda, 700487 Iasi, Romania.
  • Butnaru M; "Petru Poni" Institute of Macromolecular Chemistry, 41A Aleea Gr. GhicaVoda, 700487 Iasi, Romania.
  • Rîmbu CM; Department of Biomedical Sciences, "Grigore T. Popa" University of Medicine and Pharmacy, 9-13, Kogalniceanu Street, 700115 Iasi, Romania.
  • Enache AA; Department of Public Health, Faculty of Veterinary Medicine, Iasi University of Life Sciences (IULS), Mihail Sadoveanu Alley no. 8, 700490 Iasi, Romania.
  • Aflori M; S.C. Apel Laser S.R.L., 25, Vanatorilor Street, Mogosoaia, 077135 Ilfov, Romania.
Materials (Basel) ; 15(7)2022 Mar 28.
Article in En | MEDLINE | ID: mdl-35407829
ABSTRACT
In this study, we aim to obtain biomaterials with antibacterial properties by combining poly(vinyl alcohol) with the extracts obtained from various selected plants from Romania. Natural herbal extracts of freshly picked flowers of the lavender plant (Lavandula angustifolia) and leaves of the peppermint plant (Mentha piperita), hemp plant (Cannabis sativa L.), verbena plant (Verbena officinalis) and sage plant (Salvia officinalis folium) were selected after an intensive analyzing of diverse medicinal plants often used as antibacterial and healing agents from the country flora. The plant extracts were characterized by different methods such as totals of phenols and flavonoids content and UV-is spectroscopy. The highest amounts of the total phenolic and flavonoid contents, respectively, were recorded for Salvia officinalis. Moreover, the obtained films of poly(vinyl alcohol) (PVA) loaded with plant extracts were studied concerning the surface properties and their antibacterial or cytotoxicity activity. The Attenuated Total Reflection Fourier Transform Infrared analysis described the successfully incorporation of each plant extract in the poly(vinyl alcohol) matrix, while the profilometry demonstrated the enhanced surface properties. The results showed that the plant extracts conferred significant antibacterial effects to films toward Staphylococcus aureus and Escherichia coli and are not toxic against fibroblastic cells from the rabbit.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Materials (Basel) Year: 2022 Document type: Article Affiliation country: Romania

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Materials (Basel) Year: 2022 Document type: Article Affiliation country: Romania