Effect of Chemotherapy Cytarabine and Acute Myeloid Leukemia on the Development of Spermatogenesis at the Adult Age of Immature Treated Mice.

Khaleel, Bara'ah; Lunenfeld, Eitan; Kapelushnik, Joseph; Huleihel, Mahmoud

Khaleel, Bara'ah; Lunenfeld, Eitan; Kapelushnik, Joseph; Huleihel, Mahmoud.

Affiliation

Khaleel B; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Lunenfeld E; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Kapelushnik J; Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.
Huleihel M; The Center of Advanced Research and Education in Reproduction (CARER), Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva 8410501, Israel.

Int J Mol Sci ; 23(7)2022 Apr 04.

Article in En | MEDLINE | ID: mdl-35409373

Subject(s)

Cytarabine; Leukemia, Myeloid, Acute; Adult; Animals; Child; Cytarabine/metabolism; Cytarabine/pharmacology; Cytarabine/therapeutic use; Glial Cell Line-Derived Neurotrophic Factor/metabolism; Humans; Interleukin-6/metabolism; Leukemia, Myeloid, Acute/drug therapy; Leukemia, Myeloid, Acute/metabolism; Male; Mice; RNA/metabolism; Seminiferous Tubules/metabolism; Spermatogenesis; Spermatogonia/metabolism; Testis/metabolism; Tumor Microenvironment

Key words

acute myeloid leukemia (AML); apoptosis; chemotherapy; immature mice; male infertility; pre-pubertal; spermatogenesis; testis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Cytarabine Type of study: Prognostic_studies Limits: Adult / Animals / Child / Humans / Male Language: En Journal: Int J Mol Sci Year: 2022 Document type: Article Affiliation country: Israel Country of publication: Switzerland

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