Real-world evidence of mesenchymal stem cell therapy in knee osteoarthritis: a large prospective two-year case series.
Regen Med
; 17(6): 355-373, 2022 06.
Article
in En
| MEDLINE
| ID: mdl-35411799
The aim of this study was to assess the benefit of stem cell therapy in the treatment of mild to severe knee osteoarthritis. A total of 329 study participants with painful knee osteoarthritis undertook stem cell therapy and were followed up for two years. Stem cell therapy was well tolerated and safe. Significant pain and functional improvement were observed in all of the participant groups including those with severe bone-on-bone osteoarthritis. Participants' age and weight did not influence the clinical outcome. This study shows that stem cell therapy is an effective, safe and long-lasting treatment for knee osteoarthritis and greatly reduces knee pain and improves the function of the knee. Stem cell therapy may delay or prevent knee replacement surgery and result in significant global health and economic benefit.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoarthritis, Knee
/
Mesenchymal Stem Cell Transplantation
/
Mesenchymal Stem Cells
Type of study:
Observational_studies
Limits:
Humans
Language:
En
Journal:
Regen Med
Year:
2022
Document type:
Article
Affiliation country:
Australia
Country of publication:
United kingdom