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A structural exposé of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
Wang, Huanchen; Perera, Lalith; Jork, Nikolaus; Zong, Guangning; Riley, Andrew M; Potter, Barry V L; Jessen, Henning J; Shears, Stephen B.
Affiliation
  • Wang H; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA. huanchen.wang@nih.gov.
  • Perera L; Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
  • Jork N; Institute of Organic Chemistry, and CIBSS - the Center for Integrative Biological Signaling Studies, University of Freiburg, 79104, Freiburg, Germany.
  • Zong G; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
  • Riley AM; Drug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • Potter BVL; Drug Discovery and Medicinal Chemistry, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford, OX1 3QT, UK.
  • Jessen HJ; Institute of Organic Chemistry, and CIBSS - the Center for Integrative Biological Signaling Studies, University of Freiburg, 79104, Freiburg, Germany.
  • Shears SB; Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA. shears@niehs.nih.gov.
Nat Commun ; 13(1): 2231, 2022 04 25.
Article in En | MEDLINE | ID: mdl-35468885
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatases / Aspartic Acid Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Tyrosine Phosphatases / Aspartic Acid Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Document type: Article Affiliation country: United States Country of publication: United kingdom