Construction of Molecular Transporter Based on DNA Structure Regulation.
ACS Appl Bio Mater
; 5(5): 2122-2129, 2022 05 16.
Article
in En
| MEDLINE
| ID: mdl-35481744
ABSTRACT
This study aims to build a molecular transporter machine that is based on the microstructure regulation of DNA triplets, which can automatically search, load, target delivery, and unload target protein molecules. The design of the molecular transporter includes (1) a DNA triplet, which can recognize and load of the target protein; (2) a similar DNA triplet realizing the target transport; and (3) the signal-indicating DNA, which is connected at the target destination to achieve fixation of the target protein at the target destination. The molecular transporter machine would provide research practice and theoretical guidance for the development of DNA-based molecular machines.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
DNA
/
Exodeoxyribonucleases
Type of study:
Guideline
Language:
En
Journal:
ACS Appl Bio Mater
Year:
2022
Document type:
Article
Affiliation country:
China