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Efficient synthesis of spirooxindolyl oxazol-2(5H)-ones via palladium(ii)-catalyzed addition of arylboronic acids to nitriles.
Song, Hao; Cheng, Na; She, Li-Qin; Wu, Yi; Liao, Wei-Wei.
Affiliation
  • Song H; Department of Organic Chemistry, College of Chemistry, Jilin University Changchun 130012 P. R. China wliao@jlu.edu.cn.
  • Cheng N; Department of Organic Chemistry, College of Chemistry, Jilin University Changchun 130012 P. R. China wliao@jlu.edu.cn.
  • She LQ; Department of Organic Chemistry, College of Chemistry, Jilin University Changchun 130012 P. R. China wliao@jlu.edu.cn.
  • Wu Y; School of Pharmaceutical Science, Jilin University Changchun 130012 P. R. China wuyi19651007@163.com.
  • Liao WW; Department of Organic Chemistry, College of Chemistry, Jilin University Changchun 130012 P. R. China wliao@jlu.edu.cn.
RSC Adv ; 9(50): 29424-29428, 2019 Sep 13.
Article in En | MEDLINE | ID: mdl-35528398
A versatile synthesis of spirooxindolyl oxazol-2(5H)-ones via palladium(ii)-catalyzed addition of arylboronic acids to nitriles is described. A wide range of spirooxindolyl oxazol-2(5H)-ones and other spirocyclic frameworks incorporating the oxazol-2(5H)-one unit can be readily prepared in good to high yields under the optimal conditions.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: RSC Adv Year: 2019 Document type: Article Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: RSC Adv Year: 2019 Document type: Article Country of publication: United kingdom