Selective Inhibition of PDE4B Reduces Methamphetamine Reinforcement in Two C57BL/6 Substrains.

Honeywell, Kevin M; Doren, Eliyana Van; Szumlinski, Karen K

Honeywell, Kevin M; Doren, Eliyana Van; Szumlinski, Karen K.

Affiliation

Honeywell KM; Department of Psychological and Brain Sciences, University of California Santa Barbara, Santa Barbara, CA 93106-9660, USA.
Doren EV; Department of Psychological and Brain Sciences, University of California Santa Barbara, Santa Barbara, CA 93106-9660, USA.
Szumlinski KK; Department of Psychological and Brain Sciences, University of California Santa Barbara, Santa Barbara, CA 93106-9660, USA.

Int J Mol Sci ; 23(9)2022 Apr 28.

Article in En | MEDLINE | ID: mdl-35563262

Subject(s)

Amphetamine-Related Disorders; Central Nervous System Stimulants; Methamphetamine; Phosphodiesterase 4 Inhibitors; Amphetamine-Related Disorders/drug therapy; Amphetamine-Related Disorders/metabolism; Animals; Central Nervous System Stimulants/pharmacology; Cyclic Nucleotide Phosphodiesterases, Type 4; Female; Male; Methamphetamine/adverse effects; Mice; Mice, Inbred C57BL; Phosphodiesterase 4 Inhibitors/pharmacology; Reinforcement, Psychology; Self Administration

Key words

C57BL/6substrains; PDE4; addiction; methamphetamine; reinforcement; sex differences

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Amphetamine-Related Disorders / Phosphodiesterase 4 Inhibitors / Central Nervous System Stimulants / Methamphetamine Limits: Animals Language: En Journal: Int J Mol Sci Year: 2022 Document type: Article Affiliation country: United States Country of publication: Switzerland

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