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Lck signaling inhibition causes improvement in clinical features of psoriatic inflammation through reduction in inflammatory cytokines in CD4+ T cells in imiquimod mouse model.
Al-Harbi, Naif O; Ahmad, Sheikh F; Almutairi, Mohammed; Alanazi, Ahmed Z; Ibrahim, Khalid E; Alqarni, Saleh A; Alqahtani, Faleh; Alhazzani, Khalid; Alharbi, Metab; Alasmari, Fawaz; Nadeem, Ahmed.
Affiliation
  • Al-Harbi NO; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia. Electronic address: nharbi1@ksu.edu.sa.
  • Ahmad SF; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Almutairi M; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alanazi AZ; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Ibrahim KE; Department of Zoology, College of Science, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alqarni SA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alqahtani F; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alhazzani K; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alharbi M; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Alasmari F; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia.
  • Nadeem A; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh-11451, Saudi Arabia. Electronic address: anadeem@ksu.edu.sa.
Cell Immunol ; 376: 104531, 2022 06.
Article in En | MEDLINE | ID: mdl-35576719
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Pyrazoles / Pyrimidines / CD4-Positive T-Lymphocytes / Interleukin-17 Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Cell Immunol Year: 2022 Document type: Article Country of publication: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Pyrazoles / Pyrimidines / CD4-Positive T-Lymphocytes / Interleukin-17 Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Cell Immunol Year: 2022 Document type: Article Country of publication: Netherlands