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O-LM interneurons: Gatekeepers of pyramidal neuron activity in the hippocampus.
Poll, Stefanie; Fuhrmann, Martin.
Affiliation
  • Poll S; Neuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases, Venusberg-Campus 1/99, 53127 Bonn, Germany; Cellular Neuropathology and Cognition Group, Institute of Experimental Epileptology and Cognition Research, University of Bonn, Venusberg-Campus 1/76, 53127 Bonn, Germany.
  • Fuhrmann M; Neuroimmunology and Imaging Group, German Center for Neurodegenerative Diseases, Venusberg-Campus 1/99, 53127 Bonn, Germany. Electronic address: martin.fuhrmann@dzne.de.
Neuron ; 110(10): 1606-1608, 2022 05 18.
Article in En | MEDLINE | ID: mdl-35588712
A balanced and fine-tuned ratio of neuronal excitation and inhibition is a prerequisite for information processing. In this issue of Neuron, He et al. (2022) reveal a causal link between reduced input to local somatostatin-expressing, MeCP2-negative O-LM interneurons in CA1 and long-term memory impairment in a mouse model of Rett syndrome.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rett Syndrome / Pyramidal Cells Limits: Animals Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rett Syndrome / Pyramidal Cells Limits: Animals Language: En Journal: Neuron Journal subject: NEUROLOGIA Year: 2022 Document type: Article Affiliation country: Germany Country of publication: United States