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Fudosteine attenuates acute lung injury in septic mice by inhibiting pyroptosis via the TXNIP/NLRP3/GSDMD pathway.
He, Guangming; Chen, Keling; Wang, Hao; Li, Xiaoou; Li, Wenhao; Liu, Lian; Chen, Jun; Yang, Deqing; Hu, Jun; Xu, Dan; Wen, Fuqiang; Wang, Tao.
Affiliation
  • He G; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China; Department of Intensive Care Unit, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medici
  • Chen K; Institute of Digestive Surgery, State Key Laboratory of Biotherapy of China, West China Hospital of Sichuan University, Chengdu, China.
  • Wang H; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Li X; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Li W; West China School of Medicine, Chengdu, China.
  • Liu L; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Chen J; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Yang D; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Hu J; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Xu D; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Wen F; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China. Electronic address: wenfuqiang@scu.edu.cn.
  • Wang T; Division of Pulmonary Diseases, State Key Laboratory of Biotherapy, and Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China. Electronic address: tao.wang@scu.edu.cn.
Eur J Pharmacol ; 926: 175047, 2022 Jul 05.
Article in En | MEDLINE | ID: mdl-35609679
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / Thioredoxins / Sepsis / Cystine / Phosphate-Binding Proteins / Pore Forming Cytotoxic Proteins / Acute Lung Injury / NLR Family, Pyrin Domain-Containing 3 Protein Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2022 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / Thioredoxins / Sepsis / Cystine / Phosphate-Binding Proteins / Pore Forming Cytotoxic Proteins / Acute Lung Injury / NLR Family, Pyrin Domain-Containing 3 Protein Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2022 Document type: Article