Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis : A randomized controlled clinical trial.
Wien Klin Wochenschr
; 135(11-12): 291-300, 2023 Jun.
Article
in En
| MEDLINE
| ID: mdl-35612617
ABSTRACT
BACKGROUND:
Knee osteoarthritis (OA) is characterized by a progressive degeneration of cartilage and menisci, leading to pain and locomotor disability. Here, we aimed to assess the effect of an exercise protocol and the oral use of non-hydrolyzed collagen (UC-II) on the functionality and quality of life of women with knee OA. MATERIAL ANDMETHODS:
Individuals were divided into three groups (CG [control group]; MG [medication group]; EG [exercise group]). In the CG there was no intervention, while MG received an oral dose (1 capsule/day) of UC-II and the EG held 12 sessions of an exercise protocol.RESULTS:
In the functionality tests (6-min walk test, 6MWT and timed up and go test [TUG]) the EG (pâ¯< 0.001/pâ¯= 0.020) and MG (pâ¯= 0.010/pâ¯= 0.010) revealed a significant improvement when compared to the CG. In the analysis of quality of life by WOMAC, a significant improvement was found only in the EG (pâ¯= 0.030) when compared to the CG; the same happened in the stiffness domain (EG, pâ¯= 0.010), despite in the pain domain, both the EG (pâ¯< 0.001) and the MG (pâ¯= 0.060) were better than the CG.CONCLUSION:
Data obtained here reveal that an exercise protocol and UC-II have similar effects for functionality, despite exercise being superior in promoting the quality of life score.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Osteoarthritis, Knee
Type of study:
Clinical_trials
/
Risk_factors_studies
Aspects:
Patient_preference
Limits:
Female
/
Humans
Language:
En
Journal:
Wien Klin Wochenschr
Year:
2023
Document type:
Article
Affiliation country:
Brazil