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A pitfall in hemoglobin A1c measurement with high performance liquid chromatography method in the diagnosis of onset of fulminant type 1 diabetes mellitus.
Oe, Yasuharu; Anno, Takatoshi; Katsuhara, Yukari; Sugahara, Ryo; Kobayashi, Miki; Yakusue, Mieko; Tamura, Masayo; Kimura, Yukiko; Kawasaki, Fumiko; Kaku, Kohei; Kaneto, Hideaki; Kitanaka, Akira.
Affiliation
  • Oe Y; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Anno T; Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.
  • Katsuhara Y; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Sugahara R; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Kobayashi M; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Yakusue M; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Tamura M; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
  • Kimura Y; Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.
  • Kawasaki F; Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.
  • Kaku K; Department of General Internal Medicine 1, Kawasaki Medical School, Okayama, Japan.
  • Kaneto H; Department of Diabetes, Endocrinology and Metabolism, Kawasaki Medical School, Kurashiki, Japan.
  • Kitanaka A; Department of Clinical Laboratory, Kawasaki Medical School General Medical Center, Okayama, Japan.
J Diabetes Investig ; 13(11): 1943-1944, 2022 Nov.
Article in En | MEDLINE | ID: mdl-35620974
We showed a case with the onset of fulminant type 1 diabetes mellitus (FT1DM) whose HbA1c could not be measured with HPLC method. We think that the reason why his HbA1c was not be detected was associated with the presence of labile hemoglobin A1c (LHbA1c). These result mean that it is possible that LHbA1c can bring about a pitfall on HPLC method in diagnosis of onset of FT1DM.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Diabetes Investig Year: 2022 Document type: Article Affiliation country: Japan Country of publication: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 1 Type of study: Diagnostic_studies Limits: Humans Language: En Journal: J Diabetes Investig Year: 2022 Document type: Article Affiliation country: Japan Country of publication: Japan