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Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease.
Alhashimi, Rana T; Ghatge, Mohini S; Donkor, Akua K; Deshpande, Tanvi M; Anabaraonye, Nancy; Alramadhani, Dina; Danso-Danquah, Richmond; Huang, Boshi; Zhang, Yan; Musayev, Faik N; Abdulmalik, Osheiza; Safo, Martin K.
Affiliation
  • Alhashimi RT; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Ghatge MS; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Donkor AK; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Deshpande TM; Vertex Pharmaceutical Incorporated, Boston, MA 02210, USA.
  • Anabaraonye N; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Alramadhani D; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Danso-Danquah R; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Huang B; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Zhang Y; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Musayev FN; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
  • Abdulmalik O; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
  • Safo MK; Department of Medicinal Chemistry and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.
Biomolecules ; 12(5)2022 05 12.
Article in En | MEDLINE | ID: mdl-35625623
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Anemia, Sickle Cell Limits: Humans Language: En Journal: Biomolecules Year: 2022 Document type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prodrugs / Anemia, Sickle Cell Limits: Humans Language: En Journal: Biomolecules Year: 2022 Document type: Article Affiliation country: United States