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Internal Validation of a Risk Scoring System for Venous Thromboembolism After Total hip or Knee Arthroplasty.
Akamine, Akihiko; Takahira, Naonobu; Kuroiwa, Masayuki; Tomizawa, Atsushi; Atsuda, Koichiro.
Affiliation
  • Akamine A; Orthopedic Surgery, Clinical Medicine, Graduate School of Medical Sciences, 12877Kitasato University, Sagamihara, Kanagawa, Japan.
  • Takahira N; Department of Pharmacy, 73444Kitasato University Hospital, Sagamihara, Kanagawa, Japan.
  • Kuroiwa M; Orthopedic Surgery, Clinical Medicine, Graduate School of Medical Sciences, 12877Kitasato University, Sagamihara, Kanagawa, Japan.
  • Tomizawa A; Physical Therapy Course, Department of Rehabilitation, 89285Kitasato University School of Allied Health Sciences, Sagamihara, Kanagawa, Japan.
  • Atsuda K; Department of Anesthesiology, 38088Kitasato University School of Medicine, Sagamihara, Kanagawa 252-0373, Japan.
Clin Appl Thromb Hemost ; 28: 10760296221103868, 2022.
Article in En | MEDLINE | ID: mdl-35642285
We developed a computerized clinical decision support system (CCDSS) for venous thromboembolism (VTE) risk assessment. We aimed to demonstrate its relevance and evaluate associations between risk level and VTE incidence in patients undergoing total hip/knee arthroplasty. In this case-control study, VTE was confirmed using ultrasonography/computed tomography angiography in 1098 adults at a tertiary care hospital over five years (2013-2018). Postoperative VTE incidence was classified into three risk levels (moderate, high, and highest). The overall VTE incidence was 11.7%, which increased with a risk level of 0%, 5.8%, and 12.8% in moderate-risk, high-risk, and highest-risk patients, respectively. Highest-risk patients were significantly more likely to develop VTE than high-risk patients (odds ratio [OR] 2.4; 95% confidence interval [CI] 1.2-5.5; p = 0.01). VTE development was more likely in patients with risk scores ≥4 relative to those with risk scores of 2-3 (OR 1.8; 95% CI 1.2-2.7; p = 0.003) and -1 to 1 (OR 3.3; 95% CI 1.6-7.7; p < 0.001). This study indicates that risk level and VTE incidence are associated; our scoring system appears useful for patients undergoing total hip/knee arthroplasty.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthroplasty, Replacement, Knee / Venous Thromboembolism Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans Language: En Journal: Clin Appl Thromb Hemost Journal subject: ANGIOLOGIA Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthroplasty, Replacement, Knee / Venous Thromboembolism Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Humans Language: En Journal: Clin Appl Thromb Hemost Journal subject: ANGIOLOGIA Year: 2022 Document type: Article Affiliation country: Japan Country of publication: United States